Adiabatic T1r/T2r/RAFFn Sequences

The CMRR software downloads have migrated to a new site!

If you have not visited this page since Dec 26, 2025, you will need to reset your password. Your username is the email address that you used to sign the MTA license agreement.

Please be aware that while Siemens C2P agreements are for the specific scanner+institution, the MTA agreement to download sequences on this site are for an individual. If your institution needs to change or add additional authorized people to download sequences, each person will need to sign the MTA agreement and then CMRR will create an account on this site.

This sequence package contains the binary files for Multi slice adiabatic T1ρ, T2ρ and RAFFn relaxation mapping sequences with segmented GRE readout and parallel imaging. The current version of this sequence only supports Siemens scanners using the platform VB17.

License

Obtaining a license

The available supported software versions are listed below. If you are interested in obtaining these sequences, please follow this process to obtain a CMRR license:

  1. Obtain authorization from your Siemens Regional Collaboration Manager for the specific software you would like to license. 
    1. Contact your Siemens Regional Collaboration Manager for authorization. Please ask them to use the following text in the agreement: "developed by Dr. Shalom Michaeli and colleagues (“DEVELOPER”), employees of the University of Minnesota." If you are experiencing any delays working with your Siemens Regional Collaboration Manager please contact Colin Giambrone (colin.giambrone@siemens-healthineers.com). 
    2. Send the completed authorization form to Shalom Michaeli
  2. Select the license from the OTC website and complete the license agreement.
  3. CMRR will send you your account information and instructions for downloading the software.

Please note that the entire licensing process may take up to two weeks to process.

Once you have executed a C2P agreement and have been given an access password, the sequence binaries can be downloaded here by selecting the desired release number.

Note: The C2P agreement in step 1 applies to the institution (scanner), whereas the MTA agreement in step 2 applies to an individual. If someone else at your institution has historically been the download contact for sequences and you would also like download access, please sign the MTA agreement and CMRR will create a download account for you.

Citation

If you publish or present results obtained using the software or sequences in this package, please acknowledge the researchers who developed the sequences using the following language:

Liimatainen T, et al. MRI contrasts in high rank rotating frames. Magn Reson Med. 2015; 73:254-62. doi: 10.1002/mrm.25129

Michaeli S, et al. T1rho MRI contrast in the human brain: modulation of the longitudinal rotating frame relaxation shutter-speed during an adiabatic RF pulse. J Magn Reson. 2006; 181:135-47. doi: 10.1016/j.jmr.2006.04.002

Michaeli S, et al. Transverse relaxation in the rotating frame induced by chemical exchange. J Magn Reson. 2004; 169:293-9. doi: 10.1016/j.jmr.2004.05.010

Contact

If you have noticed a bug or have a request for a new feature in a future release, please contact

Shalom Michaeli. Be sure to include the sequence variant and the model of scanner you are using in the problem description.

Download

Please contact Shalom Michaeli to obtain access to this software package.


References

  1. Liimatainen T, et al. MRI contrasts in high rank rotating frames. Magn Reson Med. 2015; 73:254-62. doi: 10.1002/mrm.25129

  2. Michaeli S, et al. T1rho MRI contrast in the human brain: modulation of the longitudinal rotating frame relaxation shutter-speed during an adiabatic RF pulse. J Magn Reson. 2006; 181:135-47. doi: 10.1016/j.jmr.2006.04.002

  3. Michaeli S, et al. Transverse relaxation in the rotating frame induced by chemical exchange. J Magn Reson. 2004; 169:293-9. doi: 10.1016/j.jmr.2004.05.010

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