Spectroscopy - FAST(EST)MAP

The CMRR software downloads have migrated to a new site!

If you have not visited this page since Dec 26, 2025, you will need to reset your password. Your username is the email address that you used to sign the University of Minnesota license agreement.

Please be aware that while Siemens C2P agreements are for the specific scanner+institution, the University of Minnesota license agreement to download sequences on this site is for an individual. If your institution needs to change or add additional authorized people to download sequences, each person will need to sign the license agreement and then CMRR will create an account on this site.

The CMRR Spectroscopy Package contains spectroscopy and shimming sequences, and the accompanying reconstructions developed at the CMRR. The FAST(EST)MAP and the accompanying reconstructions for B0 shimming are available for use at other institutions on compatible Siemens scanners by C2P agreement with CMRR and Siemens.

This page is for FAST(EST)MAP: Automatic 1st  and 2nd order shimming using 2D projections[8]. You may also be interested in the spectroscopy sequences such as LASER, PRESS, and STEAM or the alternate SEMI-LASER (SVS).

License

Obtaining a license

The available supported software versions are listed below. If you are interested in obtaining these sequences, please follow this process to obtain a CMRR license:

  1. Obtain authorization from your Siemens Regional Collaboration Manager for the specific software you would like to license. 
    1. Contact your Siemens Regional Collaboration Manager for authorization. Please ask them to use the following text in the agreement: "developed by Dr. Małgorzata Marjańska and colleagues (“DEVELOPER”), employees of the University of Minnesota." If you are experiencing any delays working with your Siemens Regional Collaboration Manager please contact Colin Giambrone (colin.giambrone@siemens-healthineers.com). 
    2. Send the completed authorization form to Małgorzata Marjańska
  2. Select the license from the OTC website and complete the license agreement.
  3. CMRR will send you your account information.

Please note that the entire licensing process may take up to two weeks to process.

Once you have executed a C2P agreement and have been given an access password, the sequence binaries can be downloaded from the Download link(s) below by selecting the desired release number.

Note: The C2P agreement in step 1 applies to the institution (scanner), whereas the University of Minnesota license agreement in step 2 applies to an individual. If someone else at your institution has historically been the download contact for sequences and you would also like download access, please sign the University of Minnesota license agreement and CMRR will create a download account for you.

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Citation

If you publish or present results obtained using the software or sequences in this package, please acknowledge the researchers who developed the sequences using the following language:

If you publish or present results obtained using the software or sequences in this package, please acknowledge the researchers who developed the sequences using the following language:

The FAST(EST) MAP MRS package was developed by Edward J. Auerbach and Małgorzata Marjańska and provided by the University of Minnesota under a C2P agreement.

In addition, please cite the associated references:

Gruetter R and Tkác I. Field mapping without reference scan using asymmetric echo-planar techniques. Magn Reson Med. 2000; 43:319-23. doi: 10.1002/(sici)1522-2594(200002)43:2<319::aid-mrm22>3.0.co;2-1

Contact

If you have noticed a bug or have a request for a new feature in a future release, please contact Małgorzata Marjańska. Be sure to include the sequence variant and the model of scanner you are using in the problem description.

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Download FAST(EST)MAP

FAST(EST)MAP - Version Release 2016-02

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Sequences

FAST(EST)MAP - Version Release 2014-09

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Sequences


References

  1. Marjańska M, et al. Localized 1H NMR spectroscopy in different regions of human brain in vivo at 7 T: T2 relaxation times and concentrations of cerebral metabolites. NMR Biomed. 2012; 25:332-9. doi: 10.1002/nbm.1754

  2. Klomp DW, et al. Proton spectroscopic imaging of the human prostate at 7 T. NMR Biomed. 2009; 22:495-501. doi: 10.1002/nbm.1360

  3. Tremblay S, et al. The use of magnetic resonance spectroscopy as a tool for the measurement of bi-hemispheric transcranial electric stimulation effects on primary motor cortex metabolism. J Vis Exp. 2014; (unknown volume):e51631. doi: 10.3791/51631

  4. Marjańska M, et al. Brain dynamic neurochemical changes in dystonic patients: a magnetic resonance spectroscopy study. Mov Disord. 2013; 28:201-9. doi: 10.1002/mds.25279

  5. Garwood M and DelaBarre L. The return of the frequency sweep: designing adiabatic pulses for contemporary NMR. J Magn Reson. 2001; 153:155-77. doi: 10.1006/jmre.2001.2340

  6. Mescher M, et al. Simultaneous in vivo spectral editing and water suppression. NMR Biomed. 1998; 11:266-72. doi: 10.1002/(sici)1099-1492(199810)11:6<266::aid-nbm530>3.0.co;2-j

  7. Tkác I, et al. In vivo 1H NMR spectroscopy of rat brain at 1 ms echo time. Magn Reson Med. 1999; 41:649-56. doi: 10.1002/(sici)1522-2594(199904)41:4<649::aid-mrm2>3.0.co;2-g

  8. Gruetter R and Tkác I. Field mapping without reference scan using asymmetric echo-planar techniques. Magn Reson Med. 2000; 43:319-23. doi: 10.1002/(sici)1522-2594(200002)43:2<319::aid-mrm22>3.0.co;2-1

  9. Kaiser LG, et al. Elimination of spatial interference in PRESS-localized editing spectroscopy. Magn Reson Med. 2007; 58:813-8. doi: 10.1002/mrm.21407

  10. Oz G and Tkáč I. Short-echo, single-shot, full-intensity proton magnetic resonance spectroscopy for neurochemical profiling at 4 T: validation in the cerebellum and brainstem. Magn Reson Med. 2011; 65:901-10. doi: 10.1002/mrm.22708

  11. Allaïli N, et al. Single-voxel (1)H spectroscopy in the human hippocampus at 3 T using the LASER sequence: characterization of neurochemical profile and reproducibility. NMR Biomed. 2015; 28:1209-17. doi: 10.1002/nbm.3364

  12. Deelchand DK, et al. Across-vendor standardization of semi-LASER for single-voxel MRS at 3T. NMR Biomed. 2021; 34:e4218. doi: 10.1002/nbm.4218

  13. Deelchand DK, et al. Plug-and-play advanced magnetic resonance spectroscopy. Magn Reson Med. 2022; 87:2613-2620. doi: 10.1002/mrm.29164

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